Papers

Undergraduate Students

(Names noted in bold)

Mathews, J., Chang, J., Devlin, L., and Levin, M. (2023), "Cellular Signaling Pathways as Plastic, Proto-cognitive Systems: Implications for Biomedicine", Patterns, 0(0): 100737
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Shreesha, L., and Levin, M. (2023), "Cellular Competency during Development Alters Evolutionary Dynamics in an Artificial Embryogeny Model," Entropy, 25(1), 131, doi:10.3390/e25010131
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Smiley, P., and Levin, M. (2022), "Competition for Finite Resources as Coordination Mechanism for Morphogenesis: an evolutionary algorithm study of digital embryogeny", BioSystems, 221: 104672
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Murugan, N. J., Vigran, H. J., Miller, K., Golding, A., Pham, Q. L., Sperry, M., Rasmussen-Ivey, C., Kane, A. W., Kaplan, D. L., and Levin, M. (2022), "Acute multidrug delivery via a wearable bioreactor facilitates long-term limb regeneration and functional recovery in adult nXenopus laevis," Science Advances, 8(4): abj2164
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Bischof, J., LaPalme, J., Miller, K., Morokuma, J., Williams, K., Fields, C., and Levin, M. (2021), "Formation and Spontaneous Long-Term Repatterning of Headless Planarian Flatworms,"bioRxiv
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Murugan, N., Kaltman, D., Jin, H.,Chien, M., Flores, R., Nguyen, C., Tuzoff, D., Minabutdinov, A., Kane, A., Novak, R., Ingber, D., and Levin, M. (2021), "Mechanosensation Mediates Long-Range Spatial Decision-Making in an Aneural Organism," Advanced Materials, 33(34): 2008161
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Williams, K., Bischof, J., Lee, F., Miller, K., LaPalme, J., Wolfe, B., and Levin, M. (2020), "Regulation of axial and head patterning during planarian regeneration by a commensal bacterium," Mechanisms of Development, 163: 103614
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Pai, V., Cervera, J., Mafe, S., Willocq, V., Lederer, E., and Levin, M. (2020), "HCN2 Channel-induced Rescue of Brain Teratogenesis via local and long-range bioelectric repair," Frontiers in Cellular Neuroscience, 14: 136
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Jajoo, A., Donlon, C., Shnayder, S., Levin, M., and McVey, M. (2020), "Sertraline induces DNA damage and cellular toxicity in Drosophila that can be ameliorated by antioxidants," Scientific Reports, 10: 4512
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Pezzulo, G., LaPalme, J., Durant, F., and Levin, M. (2021), Bistability of Somatic Pattern Memories: Stochastic Outcomes in Bioelectric Circuits Underlying Regeneration, Philosophical Proceedings of the Royal Society B, 376(1821): 20190765
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Emmons-Bell, M., Durant, F., Tung, A., Pietak, A., Miller, K., Kane, A., Martyniuk, C. J., Davidian, D., Morokuma, J., and Levin, M. (2019), "Regenerative Adaptation To Electrochemical Perturbation In Planaria: A Molecular Analysis Of Physiological Plasticity," iScience, 22: 147-165
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Durant, F., Bischof, J., Fields, C., Morokuma, J., LaPalme, J., Hoi, A., and Levin, M. (2019), "The role of early bioelectric signals in the regeneration of planarian anterior/posterior polarity," Biophysical Journal, 116(5): 948-961
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Busse, S. M., McMillen, P. T., and Levin, M. (2018), Cross-limb Communication During Xenopus Hind-limb Regenerative Response: Non-Local Bioelectric Injury Signals, Development, 145(19): dev164210
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Pai, V. P., Pietak, A., Willocq, V., Ye, B., Shi, N-Q., and Levin, M. (2018), "HCN2 Rescues brain defects by enforcing endogenous voltage pre-patterns," Nature Communications, 9(1): 998
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Herrera-Rincon, C., Pai, V. P., Moran, K. M., Lemire, J. M., and Levin, M. (2017), "The brain is required for normal muscle and nerve patterning during early Xenopus development," Nature Communications, 8(1): 587
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Pai, V. P., Willocq, V., Pitcairn, E. J., Lemire, J. M., Paré, J-F., Shi, N-Q., McLaughlin, K. A., and Levin, M. (2017), HCN4 Ion Channel Function is Required for Early Events that Regulate Anatomical Left-Right Patterning in a Nodal- and Lefty Asymmetric gene Expression-Independent Manner, Biology Open, 6(10): 1445-1457
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Durant, F., Morokuma, J., Fields, C., Williams, K., Adams, D. S., and Levin, M. (2017), "Long-Term, Stochastic Editing of Regenerative Anatomy via Targeting Endogenous Bioelectric Gradients," Biophysical Journal, 112(10): 2231-2243
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Blackiston, D., Khanh, V., and Levin, M. (2017), "Serotonergic stimulation induces nerve growth and promotes visual learning via posterior eye grafts in a vertebrate model of induced sensory plasticity," npj Regenerative Medicine, 2: 8
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McDowell, G., Rajadurai, S., and Levin, M. (2016), "From cytoskeletal dynamics to organ asymmetry: a nonlinear, regulative pathway underlies left-right patterning," Philosophical Transactions B, 371(1710): 20150409
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Sullivan, K. G., Emmons-Bell, M., and Levin, M. (2016), "Physiological Inputs Regulate Species-Specific Anatomy During Embryogenesis And Regeneration," Communicative & Integrative Biology, 9(4): e1192733
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Durant, F., Lobo, D., Hammelman, J., and Levin, M. (2016), "Physiological controls of large-scale patterning in planarian regeneration: a molecular and computational perspective on growth and form," Regeneration, 3(2): 78-102
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Adams, D. S., Uzel, S. G. M., Akagi, J., Wlodkowic, D., Andreeva, V., Yelick, P. C., Devitt-Lee, A., Paré, J-F., and Levin, M. (2016), "Bioelectric signaling via potassium channels: a mechanism for craniofacial dysmorphogenesis in KCNJ2-associated Andersen-Tawil Syndrome," Journal of Physiology, 594(12): 3245-3270
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Hammelman, J., Lobo, D., and Levin, M. (2016), Artificial neural networks as models of robustness in development and regeneration: stability of memory during morphological remodeling, in S. Shanmuganathan and S. Samarasinghe (Eds.), Artificial Neural Network (ANN) Modeling. Studies in Computational Intelligence, vol. 628, pp. 45-65
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Lobo, D., Hammelman, J., and Levin, M., (2016), "MoCha: molecular characterization of unknown pathways," Journal of Computational Biology, 23(4): 291-297
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Emmons-Bell, M., Durant, F., Hammelman, J., Bessonov, N., Volpert, V., Morokuma, J., Pinet, K., Adams, D. S., Pietak, A., Lobo, D., and Levin, M. (2015), "Gap junctional blockade stochastically induces different species-specific head anatomies in genetically wild-type Girardia dorotocephala flatworms," International Journal of Molecular Sciences, 16(11): 27865-27896
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Lobikin, M., Lobo, D., Blackiston, D. J., Martyniuk, C. J., Tkachenko, E., and Levin, M. (2015), "Serotonergic regulation of melanocyte conversion: A bioelectrically regulated network for stochastic all-or-none hyperpigmentation," Science Signaling, 8(397): ra99
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Lobo, D., Feldman, E. B., Shah, M., Malone, T., and Levin, M. (2014), "A bioinformatics expert system linking functional data to anatomical outcomes in limb regeneration," Regeneration, 1(2): 37-56
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Lobo, D., Feldman, E.B., Shah, M., Malone, T., and Levin, M. (2014), "Limbform: a functional ontology-based database of limb regeneration experiments," Bioinformatics, 30(24): 3598-3600
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Blackiston, D., Anderson, G. M., Rahman, N., Bieck, C., and Levin, M. (2014). "A novel method for inducing nerve growth via modulation of host resting potential," Neurotherapeutics", 12(1): 170-184
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Vandenberg, L. N., Morrie, R. D., Seebohm, G., Lemire, J. M., and Levin, M. (2013), "Rab GTPases are required for early orientation of the left-right axis in Xenopus," Mechanisms of Development, 130(4-5): 254-271
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Lobo, D., Malone, T. J., and Levin, M. (2013), "Towards a bioinformatics of patterning: a computational approach to understanding regulative morphogenesis," Biology Open, 2(2): 156-169
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Lobo, D., Malone, T.J., and Levin, M. (2013), "Planform: an application and database of graph-encoded planarian regenerative experiments," Bioinformatics, 29(8): 1098-1100
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Vandenberg, L. N., Stevenson, C., and Levin, M. (2012), "Low frequency vibrations induce malformations in two aquatic species in a frequency-, waveform-, and direction-specific manner," PLoS One, 7(12): e51473
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Levin, M., and Stevenson, C. (2012), "Regulation of cell behavior and tissue patterning by bioelectrical signals: challenges and opportunities for biomedical engineering," Annual Reviews in Biomedical Engineering, 14: 295-323
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Vandenberg, L. N., Pennarola, B. W., and Levin, M. (2011), "Low frequency vibrations disrupt left-right patterning in the Xenopus embryo," PLoS One, 6(8): e23306
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Adams, D.S., Robinson, K.R., Fukumoto, T., Yuan, S., Yelick, P.,Kuo, L., McSweeney, M., and Levin, M. (2006), "Early, H⁺-V-ATPase-dependent proton flux is necessary for consistent left-right patterning of non-mammalian vertebrates," Development, 133: 1657-1671
[F1000 rating "Exceptional"]
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Hicks, C., Sorocco, D., and Levin, M. (2006), "Automated analysis of behavior: a computer-controlled system for drug screening and the investigation of learning," Journal of Neurobiology, 66(9): 977-990
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Qiu, D., Cheng, S.M., Wozniak, L., et al. and Levin, M. (2005), "Localization and loss-of-function implicate ciliary proteins in early, cytoplasmic roles in left-right asymmetry," Developmental Dynamics, 234(1): 176-189
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