Peer-Reviewed Papers
Asymmetry
Masuelli, S., Real, S., McMillen, P., Oudin, M., Levin, M., and Roqué, M. (2023), The Yin and Yang of Breast Cancer: Ion Channels as Determinants of Left-Right Functional Differences, International Journal of Molecular Sciences, 24(13): 11121
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Masuelli, S., Sebastian, R., Campoy, E., Branham, M. T., Marzese, D. M., Matthew, S., DeBlas, G., Rodolfo, A., Levin, M., and Roque, M. (2022), When left does not seem right: epigenetic and bioelectric differences between left-and right-sided breast cancer, Molecular Medicine, 28(1): 15
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Monsoro-Burq, A.H., and Levin, M. (2018), Avian models and the study of invariant asymmetry:
how the chicken and the egg taught us to tell right from left, International Journal of Developmental Biology, 62(1-3): 63-77
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Pai, V. P., Willocq, V., Pitcairn, E. J., Lemire, J. M., Pare, J-F., Shi, N-Q., McLaughlin, K. A., and Levin, M. (2017), HCN4 Ion Channel Function is Required for Early Events that Regulate Anatomical Left-Right Patterning in a Nodal- and Lefty Asymmetric gene Expression-Independent Manner, Biology Open, 6(10): 1445-1457
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Blackiston, D. J., and Levin, M. (2017), Reversals of bodies, brains, and behavior:
quantitative analysis of laterality and its disturbance in model species, in L. J. Rogers and G. Vallortigara (Eds.), Lateralized Brain Functions: Methods in Human and Non-human Species,
"Neuromethods", W. Walz (Ed.), 122: 667-694
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Levin, M., Klar, A. J. S., and Ramsdell, A. (2016), Introduction to provocative questions in Left-Right asymmetry, Philosophical Transactions of the Royal Society B, 371(1710): 20150399
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McDowell, G., Rajadurai, S., and Levin, M. (2016), From cytoskeletal dynamics to organ asymmetry: a nonlinear, regulative pathway underlies left-right patterning,
Philosophical Transactions of the Royal Society B, 371(1710): 20150409
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Davison, A., McDowell, G. S., Holden, J. M., Johnson, H. F., Koutsovoulos, G. D., Liu, M. M., Hulpiau, P., Van Roy, F., Wade, C. W., Banerjee, R., Yang, F., Chiba, S., Davey, J. W., Jackson, D. J., Levin, M., and Blaxter, M. L. (2016), Formin Is Associated with Left-Right Asymmetry in the Pond Snail and the Frog, Current Biology, 26(5): 654-660
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McDowell, G. S., Lemire, J. M., Paré, J-F., Cammarata, G., Lowery, L. A., and Levin, M. (2016),
Conserved roles for cytoskeletal components in determining laterality, Integrative Biology, 8(3): 267-286
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Dimonte, A., Adamatzky, A., Erokhin, V., and Levin, M. (2016), On chirality of slime mould, BioSystems, 140: 23-27
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Vandenberg, L. N., Blackiston, D. J., Rea, A. C., Dore, T. M., and Levin, M. (2014),
Left-right patterning in Xenopus conjoined twin embryos requires serotonin signaling
and gap junctions, International Journal of Developmental Biology, 58(10-12): 799-809
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Vandenberg, L. N., Lemire, J. M, and Levin, M. (2013), It's Never too Early to get it Right: A Conserved Role for the Cytoskeleton in Left-Right Asymmetry, Communicative & Integrative Biology, 6(6): e27155
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Blackiston, D. J., and Levin, M. (2013), Inversion of left-right asymmetry alters performance of Xenopus tadpoles in nonlateralized cognitive tasks, Animal Behaviour, 86(2): 459-466
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Vandenberg, L. N., and Levin, M. (2013), A unified model for left-right asymmetry? Comparison and synthesis of molecular models of laterality, Developmental Biology, 379(1): 1-15
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Vandenberg, L. N., Morrie, R. D., Seebohm, G., Lemire, J. M., and Levin, M. (2013), Rab GTPases are required for early orientation of the left-right axis in Xenopus, Mechanisms of Development, 130(4-5): 254-271
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Vandenberg, L. N., Lemire, J. M., and Levin, M. (2013),Serotonin has early, cilia-independent roles in Xenopus left-right patterning, Disease Models and Mechanisms,
6(1): 261-268
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Pai, V. P., Vandenberg, L. N., Blackiston, D. J., and Levin, M. (2012), Neurally derived tissues in Xenopus laevis embryos exhibit a consistent bioelectrical left-right asymmetry, Stem Cells International, 2012: 353491
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Lobikin, M., Wang, G., Xu, J.-S., Hsieh, Y.-W., Chuang, C.-F., Lemire, J. M., and Levin, M. (2012), Early, nonciliary role for microtubule proteins in left-right patterning is conserved across kingdoms, Proceedings of the National Academy of Sciences of the United States,
109(31): 12586-12591
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Vandenberg, L. N., and Levin, M. (2012), Polarity proteins are required for left-right axis orientation and twin-twin instruction,Genesis,
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Carneiro, K., Donnet, C., Rejtar, T., Karger, B. L., Díaz, E., Kortagere, S., Lemire, J. M., and Levin, M. (2011), Histone deacetylase activity is necessary for left-right patterning during vertebrate development, BMC Developmental Biology, 11: 29
PubMed |
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Vandenberg, L. N., Pennarola, B. W., and Levin, M., (2011), Low frequency vibrations disrupt left-right patterning in the Xenopus embryo, PLoS One, 6(8): e23306
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Vandenberg, L. N., and Levin, M. (2010), Consistent left-right asymmetry cannot be Established by late organizers in Xenopus unless the late organizer is a conjoined twin,
Development, 137(7): 1095-1105
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Aw, S., Koster, J., Pearson, W., Nicols, C., Shi, N. Q., Carneiro, K., and Levin, M. (2010), The ATP-sensitive K+-channel (KATP) controls early left-right patterning in Xenopus and chick embryos, Developmental Biology, 346(1): 39-53
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Vandenberg, L. N., and Levin, M. (2010), Far from solved: a perspective on what we know about early mechanisms of left-right asymmetry, Developmental Dynamics, 239(12):
3131-3146
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Aw, S., and Levin, M. (2009), Molecular mechanisms establishing consistent left-right asymmetry during vertebrate embryogenesis, in I. E. C Sommer and R. S. Kahn (Eds.), Language Lateralization and Psychosis, Cambridge University Press: Cambridge, UK, 3-18
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Aw, S., and Levin, M. (2009), Is left-right asymmetry a form of planar cell polarity? Development, 136(3): 355-366
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Vandenberg, L., and Levin, M. (2009), Perspectives and open problems in the early phases of left-right patterning, Seminars in Cell and Developmental Biology, 20(4): 456-463
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Zhang, Y., and Levin, M. (2009), Left-right asymmetry in the chick embryo requires core planar cell polarity protein Vangl2, Genesis, 47(11): 719-728
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Morokuma, J., Blackiston, D., and Levin, M. (2008), KCNQ1 and KCNE1 K+ channel components are involved in early left-right patterning in Xenopus embryos, Cellular Physiology and Biochemistry, 21(5-6): 357-372
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Aw, S., and Levin, M. (2008), What's Left in Asymmetry? Developmental Dynamics, 237(12): 3453-3464
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Aw, S., Adams, D. S., Qiu, D., and Levin, M. (2007), H,K-ATPase protein localization and Kir4.1 function reveal concordance of three axes during early determination of left-right
asymmetry, Mechanisms of Development, 125(3-4): 353-372
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Levin, M., and Palmer, R. (2007), Left-right patterning from the inside out: widespread evidence for intracellular control, BioEssays, 29(3): 271-287
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Levin, M. (2007), Gap junctional communication in morphogenesis, Progress in Biophysics and Molecular Biology, 94(1-2): 186-206
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Oviedo, N., and Levin, M. (2007), Gap junctions provide new links in left-right patterning, Cell, 129(4): 645-647
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Hibino, T., Ishii, Y., Levin, M., and Nishino, A. (2006), Ion flow regulates left-right asymmetry in sea urchin development, Development Genes and Evolution, 216(5): 265-76
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Shimeld, S. M., and Levin, M. (2006), Evidence for the regulation of left-right asymmetry in Ciona intestinalis by ion flux, Developmental Dynamics, 235(6): 1543-1553
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Adams, D. S., Robinson, K. R., Fukumoto, T., Yuan, S., Albertson, R. C., Yelick, P., Kuo, L., McSweeney, M., and Levin, M. (2006), Early, H+-V-ATPase-dependent proton flux is necessary for consistent left-right patterning of non-mammalian vertebrates, Development, 133(9): 1657-1671
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Esser, A. T., Smith, K. C., Weaver, J. C., and Levin, M. (2006),Mathematical Model of Morphogen Electrophoresis through Gap Junctions, Developmental Dynamics, 235(8): 2144-2159
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Levin, M. (2006), Is the Early Left-Right Axis like a Plant, a Kidney, or a Neuron? The
Integration of Physiological Signals in Left-Right Asymmetry, Birth Defects Research (Part C), 78(3): 191-223
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Fukumoto, T., and Levin, M. (2005), Asymmetric expression of Syndecan-2 in early chick embryogenesis, Gene Expression Patterns, 5(4): 525-528
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Fukumoto, T., Kema, I. P., and Levin, M. (2005), Serotonin signaling is a very early step in patterning of the left-right axis in chick and frog embryos, Current Biology, 15(9): 794-803
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Nogi, T., Yuan, Y. E., Sorocco, D., Perez-Tomas, R., and Levin, M. (2005), Eye regeneration assay reveals an invariant functional left-right asymmetry in the early bilaterian, Dugesia japonica, Laterality, 10(3): 193-205
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Qiu, D., Cheng, S. M., Wozniak, L., McSweeney, M., Perrone, E., and Levin, M. (2005), Localization and loss-of-function implicates ciliary proteins in early, cytoplasmic roles in
left-right asymmetry, Developmental Dynamics, 234(1): 176-189
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Fukumoto, T., Blakely, R., and Levin, M. (2005), Serotonin transporter function is an early step in left-right patterning in chick and frog embryos, Developmental Neuroscience, 27(6): 349-363
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Levin, M. (2005), Left-right asymmetry in embryonic development: a comprehensive review, Mechanisms of Development, 122(1): 3-25
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Levin, M. (2004), The embryonic origins of left-right asymmetry, Critical Reviews in Oral Biology and Medicine, 15(4): 197-206
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Adams, D. S., and Levin, M. (2004), Early Patterning of the Left/Right Axis, in C. D. Stern (Ed.), Gastrulation: from cells to embryo, Cold Spring Harbor: New York, pp. 403-417
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Bunney, T. D., De Boer, A. H., and Levin, M. (2003), Fusicoccin signaling reveals 14-3-3 protein function as a novel step in left-right patterning during amphibian embryogenesis,
Development, 130(20): 4847-4858
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Levin, M. (2003), Motor protein control of ion flux is an early step in embryonic left-right asymmetry, BioEssays, 25(10): 1002-1010
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Levin, M., Thorlin, T., Robinson, K., Nogi, T., and Mercola, M. (2002), Asymmetries in H+/K+-ATPase and cell membrane potentials comprise a very early step in left-right patterning,
Cell, 111(1): 77-89
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Mercola, M., and Levin, M. (2001), Left-Right asymmetry determination in vertebrates, Annual Review of Cell and Developmental Biology, 17: 779-805
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Levin, M. (2001), Asymmetry of Body and Brain: Embryological and Twin Studies, in N. Smelser and P. Baltes (Eds.), International Encyclopedia of the Social and Behavioral Sciences, Elsevier: Oxford, UK, pp. 853-859
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Levin, M. (1999), Twinning and embryonic left-right asymmetry, Laterality, 4(3): 197-208
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Zhu, L., Marvin, M. J., Gardiner, A., Lassar, A. B., Mercola, M., Stern, C. D., and Levin, M. (1999), Cerberus regulates left-right asymmetry of the embryonic head and heart,
Current Biology, 9(17): 931-938
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Levin, M., and Mercola, M., (1999), Gap Junction-Mediated Transfer of Left-Right Patterning Signals in the Early Chick Blastoderm is Upstream of Shh Asymmetry in the Node, Development, 126(21): 4703-4714
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Levin, M. (1999), Left-right asymmetry in animal embryogenesis, in G. Palyi, C. Zucchi, and L. Caglioti (Eds.), Advances in Biochirality, ch. 12, pp. 137-152, Elsevier Science LTD: Oxford, UK
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Levin, M., and Mercola, M. (1998), Gap junctions are involved in the early generation of left right asymmetry, Developmental Biology, 203(1): 90-105
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Levin, M., and Mercola, M. (1998), Evolutionary conservation of mechanisms upstream of asymmetric nodal expression: Reconciling chick and Xenopus, Developmental Genetics, 23(3): 185-193
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Levin, M. (1998), Left-Right asymmetry and the chick embryo, Seminars in Cell & Developmental Biology, 9(1): 67-76
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Levin, M., and Mercola, M. (1998), The compulsion of chirality: toward an understanding of left-right asymmetry, Genes & Development, 12(6): 763-769
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Levin, M., Pagan, S., Roberts, D. J., Cooke, J., Kuehn, M. R., and Tabin, C. J. (1997),
Left/Right Patterning Signals and the Independent Regulation of Different Aspects of Situs in the Chick Embryo, Developmental Biology, 189(1): 57-67
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Levin, M., and Nascone, N. (1997), Two molecular models of initial left-right asymmetry generation, Medical Hypotheses, 49(5): 429-435
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Levin, M. (1997), Left-right asymmetry in vertebrate embryogenesis, BioEssays, 19(4): 287-296
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Levin, M., Roberts, D. J., Holmes, L. B., and Tabin, C. (1996), Laterality defects in conjoined twins, Nature, 384(6607): 321
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Levin, M., Johnson, R. L., Stern, C. D., Kuehn, M., and Tabin, C. (1995), A molecular pathway determining left-right asymmetry in chick embryogenesis, Cell, 82(5): 803-814
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